Show SIM4 / tBLASTn alignment result

PARAMETERS:
Query Sequence ID: NP_001241.1
Subject Sequence ID: ENSG00000101017
Subject Sequence type: 3

Query= gi|4507581|ref|NP_001241.1| tumor necrosis factor receptor
superfamily, member 5 isoform 1 precursor; CD40 antigen; CD40L
receptor; CD40 type II isoform; nerve growth factor receptor-related
B-lymphocyte activation molecule; B cell-associated molecule; B cell
surface antigen CD40 [Homo sapiens]
         (277 letters)

>ENSG00000101017
          Length = 11025

 Score =  112 bits (281), Expect = 1e-28
 Identities = 52/53 (98%), Positives = 53/53 (100%)
 Frame = +2

Query: 225   KAPHPKQEPQEINFPDDLPGSNTAAPVQETLHGCQPVTQEDGKESRISVQERQ 277
             +APHPKQEPQEINFPDDLPGSNTAAPVQETLHGCQPVTQEDGKESRISVQERQ
Sbjct: 10613 QAPHPKQEPQEINFPDDLPGSNTAAPVQETLHGCQPVTQEDGKESRISVQERQ 10771



 Score =  109 bits (272), Expect = 1e-27
 Identities = 48/49 (97%), Positives = 49/49 (100%)
 Frame = +2

Query: 86   NLGLRVQQKGTSETDTICTCEEGWHCTSEACESCVLHRSCSPGFGVKQI 134
            +LGLRVQQKGTSETDTICTCEEGWHCTSEACESCVLHRSCSPGFGVKQI
Sbjct: 4343 DLGLRVQQKGTSETDTICTCEEGWHCTSEACESCVLHRSCSPGFGVKQI 4489



 Score =  107 bits (267), Expect = 4e-27
 Identities = 44/46 (95%), Positives = 45/46 (97%)
 Frame = +3

Query: 41   CQPGQKLVSDCTEFTETECLPCGESEFLDTWNRETHCHQHKYCDPN 86
            C PGQKLVSDCTEFTETECLPCGESEFLDTWNRETHCHQHKYCDP+
Sbjct: 3957 CFPGQKLVSDCTEFTETECLPCGESEFLDTWNRETHCHQHKYCDPS 4094



 Score = 75.1 bits (183), Expect = 2e-17
 Identities = 33/39 (84%), Positives = 34/39 (87%)
 Frame = +2

Query: 135  ATGVSDTICEPCPVGFFSNVSSAFEKCHPWTSCETKDLV 173
            ATGVSDTICEPCPVGFFSNVSSAFEKCHPWT  +   LV
Sbjct: 4859 ATGVSDTICEPCPVGFFSNVSSAFEKCHPWTRYKHSSLV 4975



 Score = 66.6 bits (161), Expect = 8e-15
 Identities = 27/28 (96%), Positives = 28/28 (100%)
 Frame = +2

Query: 18   VHPEPPTACREKQYLINSQCCSLCQPGQ 45
            VHPEPPTACREKQYLINSQCCSLCQPG+
Sbjct: 3554 VHPEPPTACREKQYLINSQCCSLCQPGE 3637



 Score = 49.3 bits (116), Expect = 1e-09
 Identities = 22/22 (100%), Positives = 22/22 (100%)
 Frame = +2

Query: 166  SCETKDLVVQQAGTNKTDVVCG 187
            SCETKDLVVQQAGTNKTDVVCG
Sbjct: 8372 SCETKDLVVQQAGTNKTDVVCG 8437



 Score = 42.4 bits (98), Expect = 2e-07
 Identities = 18/18 (100%), Positives = 18/18 (100%)
 Frame = +3

Query: 1  MVRLPLQCVLWGCLLTAV 18
          MVRLPLQCVLWGCLLTAV
Sbjct: 78 MVRLPLQCVLWGCLLTAV 131



 Score = 27.7 bits (60), Expect = 0.004
 Identities = 11/14 (78%), Positives = 12/14 (85%)
 Frame = +1

Query: 216   KKVAKKPTNKAPHP 229
             +KVAKKPTNK  HP
Sbjct: 10063 EKVAKKPTNKVGHP 10104



 Score = 25.4 bits (54), Expect = 0.021
 Identities = 17/62 (27%), Positives = 26/62 (41%), Gaps = 2/62 (3%)
 Frame = +3

Query: 125  CSPGFGVKQIATGVSDTICEPCPVGFFSNVSSAFEKCHPWTSCETKDLVVQQAGT--NKT 182
            C PG  +    T  ++T C PC    F +  +    CH    C+     V + GT  N+ 
Sbjct: 3957 CFPGQKLVSDCTEFTETECLPCGESEFLDTWNRETHCHQHKYCDPSACAVGK-GTLGNRA 4133

Query: 183  DV 184
            D+
Sbjct: 4134 DI 4139



 Score = 23.9 bits (50), Expect = 0.061
 Identities = 10/10 (100%), Positives = 10/10 (100%)
 Frame = +1

Query: 187  GPQDRLRALV 196
            GPQDRLRALV
Sbjct: 9871 GPQDRLRALV 9900



 Score = 20.0 bits (40), Expect = 0.89
 Identities = 7/11 (63%), Positives = 9/11 (81%)
 Frame = -2

Query: 259  QPVTQEDGKES 269
            QPV ++DGK S
Sbjct: 4796 QPVARQDGKSS 4764



 Score = 20.0 bits (40), Expect = 0.89
 Identities = 12/42 (28%), Positives = 17/42 (40%)
 Frame = +2

Query: 37   CCSLCQPGQKLVSDCTEFTETECLPCGESEFLDTWNRETHCH 78
            C   C P   L +  T  ++T C PC    F +  +    CH
Sbjct: 4823 CDG*CPPPHPLPA--TGVSDTICEPCPVGFFSNVSSAFEKCH 4942



 Score = 19.2 bits (38), Expect = 1.5
 Identities = 11/30 (36%), Positives = 13/30 (43%)
 Frame = -3

Query: 20   PEPPTACREKQYLINSQCCSLCQPGQKLVS 49
            P P       QYL   QC SL Q  +  +S
Sbjct: 4114 PFPTAHALGSQYLCWWQCVSLFQVSRNSLS 4025



 Score = 19.2 bits (38), Expect = 1.5
 Identities = 12/36 (33%), Positives = 16/36 (44%)
 Frame = -3

Query: 26    CREKQYLINSQCCSLCQPGQKLVSDCTEFTETECLP 61
             CR+K+  + SQC  L    Q+          T CLP
Sbjct: 10906 CRQKRGAMPSQCQPLTLTPQQ--QQHQALWPTACLP 10805



 Score = 18.9 bits (37), Expect = 2.0
 Identities = 7/24 (29%), Positives = 10/24 (41%)
 Frame = +2

Query: 107  EGWHCTSEACESCVLHRSCSPGFG 130
            + W       ++CVL   CS   G
Sbjct: 2120 QDWSLKLSDSQTCVLFTGCSQTVG 2191



 Score = 18.1 bits (35), Expect = 3.4
 Identities = 5/9 (55%), Positives = 6/9 (66%)
 Frame = +1

Query: 38   CSLCQPGQK 46
            C LC PG +
Sbjct: 6577 CKLCLPGSR 6603



 Score = 18.1 bits (35), Expect = 3.4
 Identities = 8/22 (36%), Positives = 11/22 (50%)
 Frame = +2

Query: 61   PCGESEFLDTWNRETHCHQHKY 82
            P  +S +  T    TH H HK+
Sbjct: 6200 PSRDSTYKQT---NTHTHTHKH 6256



 Score = 17.7 bits (34), Expect = 4.4
 Identities = 5/8 (62%), Positives = 7/8 (87%)
 Frame = +3

Query: 98   ETDTICTC 105
            +T T+CTC
Sbjct: 8823 QTCTLCTC 8846



 Score = 17.7 bits (34), Expect = 4.4
 Identities = 5/8 (62%), Positives = 6/8 (75%)
 Frame = +1

Query: 37   CCSLCQPG 44
            CC L +PG
Sbjct: 8239 CCVLSEPG 8262



 Score = 17.7 bits (34), Expect = 4.4
 Identities = 21/73 (28%), Positives = 24/73 (32%), Gaps = 17/73 (23%)
 Frame = -2

Query: 40   LCQPGQKLVSDCTEFTETECLP---------CGESE--------FLDTWNRETHCHQHKY 82
            +C   Q     C + T   CLP         C  S         FL      TH  QH+ 
Sbjct: 8594 ICPDSQDKWQSC-DTTPPNCLPSPFSHPVFLCASSPPSVPTFLGFLQGPLSRTHHRQHQS 8418

Query: 83   CDPNLGLRVQQKG 95
            C   L L V Q G
Sbjct: 8417 C---LCLPVAQPG 8388



 Score = 17.7 bits (34), Expect = 4.4
 Identities = 5/5 (100%), Positives = 5/5 (100%)
 Frame = +3

Query: 11  WGCLL 15
           WGCLL
Sbjct: 555 WGCLL 569



 Score = 17.3 bits (33), Expect = 5.7
 Identities = 5/13 (38%), Positives = 7/13 (53%)
 Frame = -3

Query: 105  CEEGWHCTSEACE 117
            C    HC + +CE
Sbjct: 1774 CPPPAHCKTPSCE 1736



 Score = 17.3 bits (33), Expect = 5.7
 Identities = 5/24 (20%), Positives = 13/24 (54%)
 Frame = +1

Query: 51   CTEFTETECLPCGESEFLDTWNRE 74
            C+E     C+P   ++  D+ +++
Sbjct: 7216 CSELRSRHCIPASLAKEQDSVSKK 7287



 Score = 17.3 bits (33), Expect = 5.7
 Identities = 6/11 (54%), Positives = 8/11 (72%)
 Frame = +2

Query: 39   SLCQPGQKLVS 49
            SLC+PG   V+
Sbjct: 6530 SLCRPGWSAVA 6562



 Score = 17.3 bits (33), Expect = 5.7
 Identities = 6/15 (40%), Positives = 7/15 (46%)
 Frame = -1

Query: 164  WTSCETKDLVVQQAG 178
            WT+C        QAG
Sbjct: 4821 WTTCPAHKAASGQAG 4777



 Score = 16.9 bits (32), Expect = 7.5
 Identities = 5/8 (62%), Positives = 5/8 (62%)
 Frame = -2

Query: 164  WTSCETKD 171
            W SCE  D
Sbjct: 1442 WGSCEKSD 1419



 Score = 16.5 bits (31), Expect = 9.8
 Identities = 6/11 (54%), Positives = 6/11 (54%)
 Frame = -3

Query: 12   GCLLTAVHPEP 22
            GCLL    P P
Sbjct: 2386 GCLLVEGPPRP 2354



 Score = 16.5 bits (31), Expect = 9.8
 Identities = 5/13 (38%), Positives = 8/13 (61%)
 Frame = -1

Query: 71   WNRETHCHQHKYC 83
            W++E H    +YC
Sbjct: 3627 WHKEQH*LFIRYC 3589



 Score = 16.5 bits (31), Expect = 9.8
 Identities = 6/17 (35%), Positives = 8/17 (47%)
 Frame = +1

Query: 145  PCPVGFFSNVSSAFEKC 161
            PCP+G    +  A   C
Sbjct: 6145 PCPLGSQFFLEGAIVPC 6195



 Score = 16.5 bits (31), Expect = 9.8
 Identities = 5/9 (55%), Positives = 6/9 (66%)
 Frame = -3

Query: 138  VSDTICEPC 146
            V+ T C PC
Sbjct: 9541 VAVTTCSPC 9515


Lambda     K      H
   0.318    0.133    0.439 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6973
Number of Sequences: 0
Number of extensions: 187
Number of successful extensions: 31
Number of sequences better than 10.0: 2
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 30
length of query: 277
length of database: 3675
effective HSP length: 44
effective length of query: 233
effective length of database: 3631
effective search space:   846023
effective search space used:   846023
frameshift window, decay const: 50,  0.1
T: 13
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 31 (17.1 bits)
S2: 31 (16.5 bits)

END